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TMZ: Jon Polito, best known for role in “The Big Lebowski,” dead at 65

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HOLLYWOOD, CA - JANUARY 07: Actor Jon Polito arrives at Warner Bros. Pictures' 'Gangster Squad' premiere at Grauman's Chinese Theatre on January 7, 2013 in Hollywood, California. (Photo by Kevin Winter/Getty Images)

Jon Polito — best known for his roles in Coen Brothers films like “The Big Lebowski” and “Miller’s Crossing” — died Thursday night after being taken off life support, according to family sources.

TMZ has been told Jon was diagnosed with melanoma in 2008 — he was also suffering from arthritis and had an infection related to a recent surgery. He slipped into a coma last Sunday.

Director John McNaughton broke the news Friday morning — “Jon was a born actor and will be deeply missed by his legion of friends, fans, family and of course his long time partner, Darryl Armbruster to whom I send my condolences. R.I.P. old pal.”

The Philly native was a seasoned Hollywood vet, landing roles in nearly 100 movies. He also has several TV credits, including a recurring role on ABC’s “Modern Family.”

He was 65.