(CNN) -- While former President George W. Bush says he wants his brother Jeb to run for president in 2016, their always-blunt mother said Thursday she feels differently.
"He's by far the best qualified man, but no. I really don't," she said when asked if her son, the former Florida governor, will make a White House bid.
"I think it's a great country. There are a lot of great families, and it's not just four families or whatever. There are other people out there that are very qualified and we've had enough Bushes," she said.
Her comments came Thursday morning on NBC's "Today," as the former first lady sat alongside former first lady Laura Bush and Bush 43's twin daughters, Jenna Bush Hager (a correspondent for NBC) and Barbara Bush. The three generations were together for the George W. Bush Presidential Center dedication ceremony in Dallas.
Asked if the Bush matriarch had expressed her feelings to Jeb, Jenna Bush Hager jumped in.
"Well, now!" she said, looking somewhat shocked at her sister and mother. "Surprise!"
"He's the most qualified but I don't think he'll run," Barbara Bush added. "There are other families. He'll get all our enemies, half of our friends."
In a brief email exchange Thursday morning with Jeb Bush, CNN characterized his mother's comment as priceless. In a two-word response, Jeb wrote: "Priceless indeed!"
George W. Bush, who's stepping back into the spotlight with the opening of his presidential library, told CNN's John King in an interview that aired Wednesday that he wants his brother to run.
"Well, big Jeb, you know, he's got a decision to make. And if I could make it for him, it'd be, 'run,' but I can't," he said.
"And I don't know what he's going to do," he added. "He'd be a great candidate and a great president."
Jeb Bush hasn't ruled out a possible GOP run and won't make a decision in the near future. Asked last month by CNN's Jake Tapper if he'll decide in 2014, Bush said, "the only thing I've decided is I'm not going to think about it for 2013. It's just too far out for me personally."
According to a CNN/ORC International poll released late last month, 56% of Republicans have a favorable opinion of the former governor, with House Budget Committee Chairman Paul Ryan being the only potential 2016 GOP contender with higher marks.
If he did win the nomination, Jeb Bush might face another family legacy on the Democratic ticket should former Secretary of State Hillary Clinton, wife of former President Bill Clinton, decide to run and ultimately become her party's nominee.
CNN's John King and Paul Steinhauser contributed to this report.